© All-Russian National Academy of Mycology, 2001
© A. Sergeev, 1999-2001

  Nail growth and treatment outcome
  Outgrowth of normally-looking nail is the only criterion for clinical cure. Since that the rate of nail outgrowth is the key factor defining expected time of cure and duration of treatment course. Explaining the impact of nail outgrowth we utilize our "delta-V" concept of pathogenesis:

Here Delta-V is
a resultant forse between
fungal growth in the nail towards its proximal part (DLSO) and opposing force of the natural nail growth.
Antifungal treatment stops or slowers fungal growth, and while this is true natural nail growth moves fungi out of the nail. If nail growth is slow, more time is needed to achieve full cure.


Key growth-determining factors proposed in SCIO are the target nail location and the age of the patient.
 
   
 
 
 
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